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A high-avidity biosensor reveals plasma membrane PI(3,4)P(2) is predominantly a class I PI3K signaling product

Class I phosphoinositide 3-OH kinase (PI3K) signaling is central to animal growth and metabolism, and pathological disruption of this pathway affects cancer and diabetes. However, the specific spatial/temporal dynamics and signaling roles of its minor lipid messenger, phosphatidylinositol (3,4)-bisp...

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Detalles Bibliográficos
Autores principales:	Goulden, Brady D., Pacheco, Jonathan, Dull, Allyson, Zewe, James P., Deiters, Alexander, Hammond, Gerald R.V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400549/ https://www.ncbi.nlm.nih.gov/pubmed/30591513 http://dx.doi.org/10.1083/jcb.201809026

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