Cargando…

Autophagosome maturation: An epic journey from the ER to lysosomes

Macroautophagy involves the sequestration of cytoplasmic contents in a double-membrane autophagosome and their delivery to lysosomes for degradation. In multicellular organisms, nascent autophagosomes fuse with vesicles originating from endolysosomal compartments before forming degradative autolysos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Yan G., Zhang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400552/ https://www.ncbi.nlm.nih.gov/pubmed/30578282 http://dx.doi.org/10.1083/jcb.201810099

Ejemplares similares

AMPK contributes to autophagosome maturation and lysosomal fusion
por: Jang, Minsu, et al.
Publicado: (2018)

Machinery, regulation and pathophysiological implications of autophagosome maturation
por: Zhao, Yan G., et al.
Publicado: (2021)

Route to destruction: Autophagosomes SNARE lysosomes
por: Krämer, Helmut
Publicado: (2013)

Autophagy-receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome
por: Tumbarello, David A., et al.
Publicado: (2012)

LRRK2 at the interface of autophagosomes, endosomes and lysosomes
por: Roosen, Dorien A., et al.
Publicado: (2016)

Need an ESCRT for autophagosomal maturation?
por: Manil-Segalén, Marion, et al.
Publicado: (2012)

Epic journeys of freedom : runaway slaves of the American revolution and their global quest for liberty /
por: Pybus, Cassandra
Publicado: (2006)

Spatiotemporal analysis of axonal autophagosome–lysosome dynamics reveals limited fusion events and slow maturation
por: Cason, Sydney E., et al.
Publicado: (2022)

Acetylated microtubules are required for fusion of autophagosomes with lysosomes
por: Xie, Rui, et al.
Publicado: (2010)

BORC coordinates encounter and fusion of lysosomes with autophagosomes
por: Jia, Rui, et al.
Publicado: (2017)

The role of lysosomes and autophagosomes in frontotemporal lobar degeneration
por: Bain, H. D. C., et al.
Publicado: (2018)

Detyrosinated microtubules spatially constrain lysosomes facilitating lysosome–autophagosome fusion
por: Mohan, Nitin, et al.
Publicado: (2019)

AMPK Regulates Phagophore-to-Autophagosome Maturation
por: Barnaba, Carlo, et al.
Publicado: (2023)

Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection
por: Di Cristina, Manlio, et al.
Publicado: (2017)

Prefused lysosomes cluster on autophagosomes regulated by VAMP8
por: Chen, Qixin, et al.
Publicado: (2021)

The Itinerary of Autophagosomes: From Peripheral Formation to Kiss-and-Run Fusion with Lysosomes
por: Jahreiss, Luca, et al.
Publicado: (2008)

A reversible autophagy inhibitor blocks autophagosome–lysosome fusion by preventing Stx17 loading onto autophagosomes
por: Vats, Somya, et al.
Publicado: (2019)

Autophagosome–lysosome fusion is independent of V-ATPase-mediated acidification
por: Mauvezin, Caroline, et al.
Publicado: (2015)

The IAP family member BRUCE regulates autophagosome–lysosome fusion
por: Ebner, Petra, et al.
Publicado: (2018)

Commentary: Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection
por: Di Guardo, Giovanni
Publicado: (2017)

Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes
por: Gradzka, Sylwia, et al.
Publicado: (2018)

Lipid Droplet Contacts With Autophagosomes, Lysosomes, and Other Degradative Vesicles
por: Drizyte-Miller, Kristina, et al.
Publicado: (2020)

Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL
por: De Leo, Maria Giovanna, et al.
Publicado: (2016)

HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation
por: Zhan, Yunyan, et al.
Publicado: (2020)

HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons
por: Li, Xiao-Cheng, et al.
Publicado: (2017)

Autophagosome Biogenesis
por: Zhen, Yan, et al.
Publicado: (2023)

ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome–lysosome fusion
por: Wang, Ruoxi, et al.
Publicado: (2019)

Autophagosome Precursor Maturation Requires Homotypic Fusion
por: Moreau, Kevin, et al.
Publicado: (2011)

SNARE priming is essential for maturation of autophagosomes but not for their formation
por: Abada, Adi, et al.
Publicado: (2017)

Maturing Autophagosomes are Transported Towards the Cell Periphery
por: Hilverling, Anna, et al.
Publicado: (2021)

LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes
por: Hubert, Virginie, et al.
Publicado: (2016)

Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17
por: Matsui, Takahide, et al.
Publicado: (2018)

De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics
por: Rowland, Leslie A., et al.
Publicado: (2023)

Katnip is needed to maintain microtubule function and lysosomal delivery to autophagosomes and phagosomes
por: Starling, Georgina P., et al.
Publicado: (2023)

BRUCE silencing leads to axonal dystrophy by repressing autophagosome-lysosome fusion in Alzheimer’s disease
por: Zhang, Lu, et al.
Publicado: (2021)

Age-Related Intraneuronal Aggregation of Amyloid-β in Endosomes, Mitochondria, Autophagosomes, and Lysosomes
por: Brewer, Gregory J., et al.
Publicado: (2020)

Barbara Natterson-Horowitz and Kathryn Bowers, Wildhood: The Epic Journey from Adolescence to Adulthood in Humans and Other Animals
por: Maley, Carlo C
Publicado: (2020)

OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation
por: Itoh, Takashi, et al.
Publicado: (2011)

New Ca(2+)-dependent regulators of autophagosome maturation
por: Ghislat, Ghita, et al.
Publicado: (2012)

Swapping of interaction partners with ATG5 for autophagosome maturation
por: Kim, Jun Hoe, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_o7olbb9gnimm3rkijh3oa1qr1n