Protein transport by vesicles and tunnels

Palade’s corpus placed small vesicles as the sole means to transport proteins across stable distinct compartments of the secretory pathway. We suggest that cargo, spatial organization of secretory compartments, and the timing of fission of cargo-filled containers dictate the design of transport inte...

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Detalles Bibliográficos
Autores principales: Raote, Ishier, Malhotra, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400553/
https://www.ncbi.nlm.nih.gov/pubmed/30718263
http://dx.doi.org/10.1083/jcb.201811073
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author Raote, Ishier
Malhotra, Vivek
author_facet Raote, Ishier
Malhotra, Vivek
author_sort Raote, Ishier
collection PubMed
description Palade’s corpus placed small vesicles as the sole means to transport proteins across stable distinct compartments of the secretory pathway. We suggest that cargo, spatial organization of secretory compartments, and the timing of fission of cargo-filled containers dictate the design of transport intermediates that can be vesicles and transient direct tunnels.
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spelling pubmed-64005532019-09-04 Protein transport by vesicles and tunnels Raote, Ishier Malhotra, Vivek J Cell Biol Commentary Palade’s corpus placed small vesicles as the sole means to transport proteins across stable distinct compartments of the secretory pathway. We suggest that cargo, spatial organization of secretory compartments, and the timing of fission of cargo-filled containers dictate the design of transport intermediates that can be vesicles and transient direct tunnels. Rockefeller University Press 2019-03-04 /pmc/articles/PMC6400553/ /pubmed/30718263 http://dx.doi.org/10.1083/jcb.201811073 Text en © 2019 Raote and Malhotra http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Raote, Ishier
Malhotra, Vivek
Protein transport by vesicles and tunnels
title Protein transport by vesicles and tunnels
title_full Protein transport by vesicles and tunnels
title_fullStr Protein transport by vesicles and tunnels
title_full_unstemmed Protein transport by vesicles and tunnels
title_short Protein transport by vesicles and tunnels
title_sort protein transport by vesicles and tunnels
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400553/
https://www.ncbi.nlm.nih.gov/pubmed/30718263
http://dx.doi.org/10.1083/jcb.201811073
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