TAPPing into PIPs: A new reporter reveals the origin of plasma membrane PI(3,4)P(2)

The membrane lipid phosphatidylinositol-3,4-bisphosphate (PI(3,4)P(2)) is an important signaling effector, controlling both anabolic pathways and membrane trafficking. In this issue, Goulden et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201809026) report a new PI(3,4)P(2) probe and show th...

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Detalles Bibliográficos
Autor principal: Yudushkin, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400554/
https://www.ncbi.nlm.nih.gov/pubmed/30709853
http://dx.doi.org/10.1083/jcb.201901143
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author Yudushkin, Ivan
author_facet Yudushkin, Ivan
author_sort Yudushkin, Ivan
collection PubMed
description The membrane lipid phosphatidylinositol-3,4-bisphosphate (PI(3,4)P(2)) is an important signaling effector, controlling both anabolic pathways and membrane trafficking. In this issue, Goulden et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201809026) report a new PI(3,4)P(2) probe and show that plasma membrane PI(3,4)P(2) is a product of PI(3,4,5)P(3) dephosphorylation.
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spelling pubmed-64005542019-09-04 TAPPing into PIPs: A new reporter reveals the origin of plasma membrane PI(3,4)P(2) Yudushkin, Ivan J Cell Biol Commentaries The membrane lipid phosphatidylinositol-3,4-bisphosphate (PI(3,4)P(2)) is an important signaling effector, controlling both anabolic pathways and membrane trafficking. In this issue, Goulden et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201809026) report a new PI(3,4)P(2) probe and show that plasma membrane PI(3,4)P(2) is a product of PI(3,4,5)P(3) dephosphorylation. Rockefeller University Press 2019-03-04 /pmc/articles/PMC6400554/ /pubmed/30709853 http://dx.doi.org/10.1083/jcb.201901143 Text en © 2019 Yudushkin http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Yudushkin, Ivan
TAPPing into PIPs: A new reporter reveals the origin of plasma membrane PI(3,4)P(2)
title TAPPing into PIPs: A new reporter reveals the origin of plasma membrane PI(3,4)P(2)
title_full TAPPing into PIPs: A new reporter reveals the origin of plasma membrane PI(3,4)P(2)
title_fullStr TAPPing into PIPs: A new reporter reveals the origin of plasma membrane PI(3,4)P(2)
title_full_unstemmed TAPPing into PIPs: A new reporter reveals the origin of plasma membrane PI(3,4)P(2)
title_short TAPPing into PIPs: A new reporter reveals the origin of plasma membrane PI(3,4)P(2)
title_sort tapping into pips: a new reporter reveals the origin of plasma membrane pi(3,4)p(2)
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400554/
https://www.ncbi.nlm.nih.gov/pubmed/30709853
http://dx.doi.org/10.1083/jcb.201901143
work_keys_str_mv AT yudushkinivan tappingintopipsanewreporterrevealstheoriginofplasmamembranepi34p2

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