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The activity of Sac1 across ER–TGN contact sites requires the four-phosphate-adaptor-protein-1
Phosphatidylinositol-4-phosphate (PI4P), a phosphoinositide with key roles in the Golgi complex, is made by Golgi-associated phosphatidylinositol-4 kinases and consumed by the 4-phosphatase Sac1 that, instead, is an ER membrane protein. Here, we show that the contact sites between the ER and the TGN...
Autores principales: | Venditti, Rossella, Masone, Maria Chiara, Rega, Laura Rita, Di Tullio, Giuseppe, Santoro, Michele, Polishchuk, Elena, Serrano, Ivan Castello, Olkkonen, Vesa M., Harada, Akihiro, Medina, Diego L., La Montagna, Raffaele, De Matteis, Maria Antonietta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400556/ https://www.ncbi.nlm.nih.gov/pubmed/30659099 http://dx.doi.org/10.1083/jcb.201812021 |
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