Cargando…
Activation mechanism of ATP-sensitive K(+) channels explored with real-time nucleotide binding
The response of ATP-sensitive K(+) channels (K(ATP)) to cellular metabolism is coordinated by three classes of nucleotide binding site (NBS). We used a novel approach involving labeling of intact channels in a native, membrane environment with a non-canonical fluorescent amino acid and measurement (...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400584/ https://www.ncbi.nlm.nih.gov/pubmed/30789344 http://dx.doi.org/10.7554/eLife.41103 |