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Scar tissue to lung cancer; pathways and treatment
Lung cancer still remains diagnosed at a late stage although we have novel diagnostic techniques at our disposal. However; for metastatic disease we have novel therapies based on pharmacogenomics. Tumor heterogenity provides us different treatments. There are several reasons for carcinogenesis; fibr...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400809/ https://www.ncbi.nlm.nih.gov/pubmed/30854086 http://dx.doi.org/10.7150/jca.30300 |
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author | Sapalidis, Konstantinos Sardeli, Chrysanthi Pavlidis, Efstathios Koimtzis, Georgios Koulouris, Charilaos Michalopoulos, Nikolaos Mantalovas, Stylianos Tsiouda, Theodora Passos, Ioannis Kosmidis, Christoforos Giannakidis, Dimitrios Surlin, Valeriu Katsaounis, Athanasios Alexandrou, Vyron Amaniti, Aikaterini Zarogoulidis, Paul Huang, Haidong Li, Qiang Mogoanta, Stelian Kesisoglou, Isaac |
author_facet | Sapalidis, Konstantinos Sardeli, Chrysanthi Pavlidis, Efstathios Koimtzis, Georgios Koulouris, Charilaos Michalopoulos, Nikolaos Mantalovas, Stylianos Tsiouda, Theodora Passos, Ioannis Kosmidis, Christoforos Giannakidis, Dimitrios Surlin, Valeriu Katsaounis, Athanasios Alexandrou, Vyron Amaniti, Aikaterini Zarogoulidis, Paul Huang, Haidong Li, Qiang Mogoanta, Stelian Kesisoglou, Isaac |
author_sort | Sapalidis, Konstantinos |
collection | PubMed |
description | Lung cancer still remains diagnosed at a late stage although we have novel diagnostic techniques at our disposal. However; for metastatic disease we have novel therapies based on pharmacogenomics. Tumor heterogenity provides us different treatments. There are several reasons for carcinogenesis; fibrosis and scar tissue provides an environment that induces malignancy. In the current review we will try and elucidate the pathways involved from scar tissue to carcinogenesis. |
format | Online Article Text |
id | pubmed-6400809 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-64008092019-03-08 Scar tissue to lung cancer; pathways and treatment Sapalidis, Konstantinos Sardeli, Chrysanthi Pavlidis, Efstathios Koimtzis, Georgios Koulouris, Charilaos Michalopoulos, Nikolaos Mantalovas, Stylianos Tsiouda, Theodora Passos, Ioannis Kosmidis, Christoforos Giannakidis, Dimitrios Surlin, Valeriu Katsaounis, Athanasios Alexandrou, Vyron Amaniti, Aikaterini Zarogoulidis, Paul Huang, Haidong Li, Qiang Mogoanta, Stelian Kesisoglou, Isaac J Cancer Review Lung cancer still remains diagnosed at a late stage although we have novel diagnostic techniques at our disposal. However; for metastatic disease we have novel therapies based on pharmacogenomics. Tumor heterogenity provides us different treatments. There are several reasons for carcinogenesis; fibrosis and scar tissue provides an environment that induces malignancy. In the current review we will try and elucidate the pathways involved from scar tissue to carcinogenesis. Ivyspring International Publisher 2019-01-30 /pmc/articles/PMC6400809/ /pubmed/30854086 http://dx.doi.org/10.7150/jca.30300 Text en © Ivyspring International Publisher This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions. |
spellingShingle | Review Sapalidis, Konstantinos Sardeli, Chrysanthi Pavlidis, Efstathios Koimtzis, Georgios Koulouris, Charilaos Michalopoulos, Nikolaos Mantalovas, Stylianos Tsiouda, Theodora Passos, Ioannis Kosmidis, Christoforos Giannakidis, Dimitrios Surlin, Valeriu Katsaounis, Athanasios Alexandrou, Vyron Amaniti, Aikaterini Zarogoulidis, Paul Huang, Haidong Li, Qiang Mogoanta, Stelian Kesisoglou, Isaac Scar tissue to lung cancer; pathways and treatment |
title | Scar tissue to lung cancer; pathways and treatment |
title_full | Scar tissue to lung cancer; pathways and treatment |
title_fullStr | Scar tissue to lung cancer; pathways and treatment |
title_full_unstemmed | Scar tissue to lung cancer; pathways and treatment |
title_short | Scar tissue to lung cancer; pathways and treatment |
title_sort | scar tissue to lung cancer; pathways and treatment |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400809/ https://www.ncbi.nlm.nih.gov/pubmed/30854086 http://dx.doi.org/10.7150/jca.30300 |
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