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Scar tissue to lung cancer; pathways and treatment

Lung cancer still remains diagnosed at a late stage although we have novel diagnostic techniques at our disposal. However; for metastatic disease we have novel therapies based on pharmacogenomics. Tumor heterogenity provides us different treatments. There are several reasons for carcinogenesis; fibr...

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Autores principales: Sapalidis, Konstantinos, Sardeli, Chrysanthi, Pavlidis, Efstathios, Koimtzis, Georgios, Koulouris, Charilaos, Michalopoulos, Nikolaos, Mantalovas, Stylianos, Tsiouda, Theodora, Passos, Ioannis, Kosmidis, Christoforos, Giannakidis, Dimitrios, Surlin, Valeriu, Katsaounis, Athanasios, Alexandrou, Vyron, Amaniti, Aikaterini, Zarogoulidis, Paul, Huang, Haidong, Li, Qiang, Mogoanta, Stelian, Kesisoglou, Isaac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400809/
https://www.ncbi.nlm.nih.gov/pubmed/30854086
http://dx.doi.org/10.7150/jca.30300
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author Sapalidis, Konstantinos
Sardeli, Chrysanthi
Pavlidis, Efstathios
Koimtzis, Georgios
Koulouris, Charilaos
Michalopoulos, Nikolaos
Mantalovas, Stylianos
Tsiouda, Theodora
Passos, Ioannis
Kosmidis, Christoforos
Giannakidis, Dimitrios
Surlin, Valeriu
Katsaounis, Athanasios
Alexandrou, Vyron
Amaniti, Aikaterini
Zarogoulidis, Paul
Huang, Haidong
Li, Qiang
Mogoanta, Stelian
Kesisoglou, Isaac
author_facet Sapalidis, Konstantinos
Sardeli, Chrysanthi
Pavlidis, Efstathios
Koimtzis, Georgios
Koulouris, Charilaos
Michalopoulos, Nikolaos
Mantalovas, Stylianos
Tsiouda, Theodora
Passos, Ioannis
Kosmidis, Christoforos
Giannakidis, Dimitrios
Surlin, Valeriu
Katsaounis, Athanasios
Alexandrou, Vyron
Amaniti, Aikaterini
Zarogoulidis, Paul
Huang, Haidong
Li, Qiang
Mogoanta, Stelian
Kesisoglou, Isaac
author_sort Sapalidis, Konstantinos
collection PubMed
description Lung cancer still remains diagnosed at a late stage although we have novel diagnostic techniques at our disposal. However; for metastatic disease we have novel therapies based on pharmacogenomics. Tumor heterogenity provides us different treatments. There are several reasons for carcinogenesis; fibrosis and scar tissue provides an environment that induces malignancy. In the current review we will try and elucidate the pathways involved from scar tissue to carcinogenesis.
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spelling pubmed-64008092019-03-08 Scar tissue to lung cancer; pathways and treatment Sapalidis, Konstantinos Sardeli, Chrysanthi Pavlidis, Efstathios Koimtzis, Georgios Koulouris, Charilaos Michalopoulos, Nikolaos Mantalovas, Stylianos Tsiouda, Theodora Passos, Ioannis Kosmidis, Christoforos Giannakidis, Dimitrios Surlin, Valeriu Katsaounis, Athanasios Alexandrou, Vyron Amaniti, Aikaterini Zarogoulidis, Paul Huang, Haidong Li, Qiang Mogoanta, Stelian Kesisoglou, Isaac J Cancer Review Lung cancer still remains diagnosed at a late stage although we have novel diagnostic techniques at our disposal. However; for metastatic disease we have novel therapies based on pharmacogenomics. Tumor heterogenity provides us different treatments. There are several reasons for carcinogenesis; fibrosis and scar tissue provides an environment that induces malignancy. In the current review we will try and elucidate the pathways involved from scar tissue to carcinogenesis. Ivyspring International Publisher 2019-01-30 /pmc/articles/PMC6400809/ /pubmed/30854086 http://dx.doi.org/10.7150/jca.30300 Text en © Ivyspring International Publisher This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Review
Sapalidis, Konstantinos
Sardeli, Chrysanthi
Pavlidis, Efstathios
Koimtzis, Georgios
Koulouris, Charilaos
Michalopoulos, Nikolaos
Mantalovas, Stylianos
Tsiouda, Theodora
Passos, Ioannis
Kosmidis, Christoforos
Giannakidis, Dimitrios
Surlin, Valeriu
Katsaounis, Athanasios
Alexandrou, Vyron
Amaniti, Aikaterini
Zarogoulidis, Paul
Huang, Haidong
Li, Qiang
Mogoanta, Stelian
Kesisoglou, Isaac
Scar tissue to lung cancer; pathways and treatment
title Scar tissue to lung cancer; pathways and treatment
title_full Scar tissue to lung cancer; pathways and treatment
title_fullStr Scar tissue to lung cancer; pathways and treatment
title_full_unstemmed Scar tissue to lung cancer; pathways and treatment
title_short Scar tissue to lung cancer; pathways and treatment
title_sort scar tissue to lung cancer; pathways and treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400809/
https://www.ncbi.nlm.nih.gov/pubmed/30854086
http://dx.doi.org/10.7150/jca.30300
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