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Pseudomonas aeruginosa Exoprotein-Induced Barrier Disruption Correlates With Elastase Activity and Marks Chronic Rhinosinusitis Severity

Background: Pseudomonas aeruginosa causes severe chronic respiratory diseases and is associated with recalcitrant chronic rhinosinusitis (CRS). P. aeruginosa exoproteins contain virulence factors and play important roles in the pathogenicity of P. aeruginosa, however their role in CRS pathophysiolog...

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Detalles Bibliográficos
Autores principales: Li, Jian, Ramezanpour, Mahnaz, Fong, Stephanie A., Cooksley, Clare, Murphy, Jae, Suzuki, Masanobu, Psaltis, Alkis J., Wormald, Peter John, Vreugde, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400838/
https://www.ncbi.nlm.nih.gov/pubmed/30873390
http://dx.doi.org/10.3389/fcimb.2019.00038