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Current Murine Models and New Developments in H3K27M Diffuse Midline Gliomas

Diffuse Midline Gliomas with Histone 3-Lysine-27-Methionine (H3K27M) mutation constitute the majority of Diffuse Intrinsic Pontine Glioma (DIPG), which is the most aggressive form of pediatric glioma with a dire prognosis. DIPG are lethal tumors found in younger children with a median survival <1...

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Detalles Bibliográficos
Autores principales: Welby, John P., Kaptzan, Tatiana, Wohl, Anton, Peterson, Timothy E., Raghunathan, Aditya, Brown, Desmond A., Gupta, Shiv K., Zhang, Liang, Daniels, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400847/
https://www.ncbi.nlm.nih.gov/pubmed/30873381
http://dx.doi.org/10.3389/fonc.2019.00092