Cargando…

The Molecular Mechanism of Transforming Growth Factor-β Signaling for Intestinal Fibrosis: A Mini-Review

Inflammatory bowel disease is known as the most chronic inflammatory disorder in colon, which subsequently progresses to intestinal obstruction and fistula formation. Many studies to date for the treatment of IBD have been focused on inflammation. However, most of the anti-inflammatory agents do not...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yun, Sun-Mi, Kim, Seok-Ho, Kim, Eun-Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400889/ https://www.ncbi.nlm.nih.gov/pubmed/30873033 http://dx.doi.org/10.3389/fphar.2019.00162

Ejemplares similares

Xanthohumol Interferes with the Activation of TGF-β Signaling in the Process Leading to Intestinal Fibrosis
por: Yun, Sun-Mi, et al.
Publicado: (2022)

Micellized Protein Transduction Domain-Bone Morphogenetic Protein-7 Efficiently Blocks Renal Fibrosis Via Inhibition of Transforming Growth Factor-Beta–Mediated Epithelial–Mesenchymal Transition
por: Kim, Seonghun, et al.
Publicado: (2020)

Low-Dose of Intrapulmonary Pirfenidone Improves Human Transforming Growth Factorβ1-Driven Lung Fibrosis
por: Okano, Tomohito, et al.
Publicado: (2020)

Latent Transforming Growth Factor-β Binding Protein-2 Regulates Lung Fibroblast-to-Myofibroblast Differentiation in Pulmonary Fibrosis via NF-κB Signaling
por: Zou, Menglin, et al.
Publicado: (2021)

Transforming Growth Factor-Beta (TGF-β) Signaling in Cancer-A Betrayal Within
por: Baba, Abdul Basit, et al.
Publicado: (2022)

Stachydrine Ameliorates Cardiac Fibrosis Through Inhibition of Angiotensin II/Transformation Growth Factor β1 Fibrogenic Axis
por: Liu, Xiao, et al.
Publicado: (2019)

Metformin Ameliorates Chronic Colitis-Related Intestinal Fibrosis via Inhibiting TGF-β1/Smad3 Signaling
por: Wang, Ying, et al.
Publicado: (2022)

Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis
por: Keenan, Christine R., et al.
Publicado: (2018)

TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis
por: Yu, Xiao-Yong, et al.
Publicado: (2022)

Honokiol Alleviates Hypertrophic Scar by Targeting Transforming Growth Factor-β/Smad2/3 Signaling Pathway
por: Zhao, Danyang, et al.
Publicado: (2017)

Fluoxetine Prevents Aβ(1-42)-Induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factor-β1
por: Caraci, Filippo, et al.
Publicado: (2016)

Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis
por: Walton, Kelly L., et al.
Publicado: (2017)

Kahweol decreases hepatic fibrosis by inhibiting the expression of connective tissue growth factor via the transforming growth factor-beta signaling pathway
por: Seo, Hye-Young, et al.
Publicado: (2017)

Millet seed oil activates β–catenin signaling and promotes hair growth
por: Lee, Eunyoung, et al.
Publicado: (2023)

Autophagy attenuates tubulointerstital fibrosis through regulating transforming growth factor-β and NLRP3 inflammasome signaling pathway
por: Nam, Sun Ah, et al.
Publicado: (2019)

Kinsenoside Protects Against Radiation-Induced Liver Fibrosis via Downregulating Connective Tissue Growth Factor Through TGF-β1 Signaling
por: Nie, Xiaoqi, et al.
Publicado: (2022)

Ursolic Acid Improves Intestinal Damage and Bacterial Dysbiosis in Liver Fibrosis Mice
por: Wan, Si-Zhe, et al.
Publicado: (2019)

Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling
por: Huang, Qian, et al.
Publicado: (2022)

Curcumin Inhibits Transforming Growth Factor β Induced Differentiation of Mouse Lung Fibroblasts to Myofibroblasts
por: Liu, Daishun, et al.
Publicado: (2016)

Drug like HSP27 cross linkers with chromenone structure ameliorates pulmonary fibrosis
por: Yoo, Young Jo, et al.
Publicado: (2023)

Autophagy in intestinal fibrosis: relevance in inflammatory bowel disease
por: Macias-Ceja, Dulce C., et al.
Publicado: (2023)

Together and apart: inhibition of DNA synthesis by connexin-43 and its relationship to transforming growth factor β
por: Jeyaraman, Maya M., et al.
Publicado: (2013)

Effects of Nervilia fordii Extract on Pulmonary Fibrosis Through TGF-β/Smad Signaling Pathway
por: Yao, Yufeng, et al.
Publicado: (2021)

Mechanism of action of non-coding RNAs and traditional Chinese medicine in myocardial fibrosis: Focus on the TGF-β/Smad signaling pathway
por: Li, Chunjun, et al.
Publicado: (2023)

Molecular Mechanisms and Potential New Therapeutic Drugs for Liver Fibrosis
por: Wang, Fa-Da, et al.
Publicado: (2022)

Transforming growth factor–β in tissue fibrosis
por: Frangogiannis, Nikolaos G.
Publicado: (2020)

Targeting the Transforming Growth Factor-β Signaling in Cancer Therapy
por: Sheen, Yhun Yhong, et al.
Publicado: (2013)

Catalpol Protects Against Pulmonary Fibrosis Through Inhibiting TGF-β1/Smad3 and Wnt/β-Catenin Signaling Pathways
por: Yang, Fan, et al.
Publicado: (2021)

Targeting the Wnt/β-Catenin Signaling Pathway as a Potential Therapeutic Strategy in Renal Tubulointerstitial Fibrosis
por: Li, Shan-Shan, et al.
Publicado: (2021)

Blueberry Juice Attenuates Pulmonary Fibrosis via Blocking the TGF-β1/Smad Signaling Pathway
por: Li, Yali, et al.
Publicado: (2022)

Emerging Therapeutic Strategies for Attenuating Tubular EMT and Kidney Fibrosis by Targeting Wnt/β-Catenin Signaling
por: Hu, Lichao, et al.
Publicado: (2022)

Metformin prevents peritendinous fibrosis by inhibiting transforming growth factor-β signaling
por: Zheng, Wei, et al.
Publicado: (2017)

Regulation of transforming growth factor-β signalling by SUMOylation and its role in fibrosis
por: Wang, Xinyi, et al.
Publicado: (2021)

Ionizing Radiation-Induced Cellular Senescence in Normal, Non-transformed Cells and the Involved DNA Damage Response: A Mini Review
por: Li, Mengqian, et al.
Publicado: (2018)

Rho-Kinase 1/2 Inhibition Prevents Transforming Growth Factor-β-Induced Effects on Pulmonary Remodeling and Repair
por: Wu, Xinhui, et al.
Publicado: (2021)

Ultrasonographic Evaluation of Intestinal Fibrosis and Inflammation in Crohn’s Disease. The State of the Art
por: Ferretti, Francesca, et al.
Publicado: (2021)

Arecoline Enhances Phosphodiesterase 4A Activity to Promote Transforming Growth Factor-β-Induced Buccal Mucosal Fibroblast Activation via cAMP-Epac1 Signaling Pathway
por: Zhang, Bo, et al.
Publicado: (2021)

Dec1 Deficiency Ameliorates Pulmonary Fibrosis Through the PI3K/AKT/GSK-3β/β-Catenin Integrated Signaling Pathway
por: Hu, Xingxing, et al.
Publicado: (2022)

The anti-leukemia activity and mechanisms of shikonin: a mini review
por: Dong, Han, et al.
Publicado: (2023)

A Glycoengineered Interferon-β Mutein (R27T) Generates Prolonged Signaling by an Altered Receptor-Binding Kinetics
por: Lee, Saehyung, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_gra5p5gs3vop03ekbe9r3ndf01