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Carbocisteine Improves Histone Deacetylase 2 Deacetylation Activity via Regulating Sumoylation of Histone Deacetylase 2 in Human Tracheobronchial Epithelial Cells
Histone deacetylase (HDAC) 2 plays a vital role in modifying histones to mediate inflammatory responses, while HDAC2 itself is commonly regulated by post-translational modifications. Small ubiquitin-related modifier (SUMO), as an important PTM factor, is involved in the regulation of multiple protei...
Autores principales: | Song, Yun, Chi, Dan-Yi, Yu, Ping, Lu, Juan-Juan, Xu, Jian-Rong, Tan, Pan-Pan, Wang, Bin, Cui, Yong-Yao, Chen, Hong-Zhuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400890/ https://www.ncbi.nlm.nih.gov/pubmed/30873037 http://dx.doi.org/10.3389/fphar.2019.00166 |
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