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Rapid Downregulation of DAB2 by Toll-Like Receptor Activation Contributes to a Pro-Inflammatory Switch in Activated Dendritic Cells
Dendritic cells (DCs) are pivotal in regulating tolerogenic as well as immunogenic responses against microorganisms by directing both the innate and adaptive immune response. In health, phenotypically different DC subsets found in the gut mucosa are maintained in their tolerogenic state but switch t...
Autores principales: | Figliuolo da Paz, Vanessa, Jamwal, Deepa R., Gurney, Michael, Midura-Kiela, Monica, Harrison, Christy A., Cox, Christopher, Wilson, Jean M., Ghishan, Fayez K., Kiela, Pawel R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400992/ https://www.ncbi.nlm.nih.gov/pubmed/30873168 http://dx.doi.org/10.3389/fimmu.2019.00304 |
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