Anaphylactic Reaction to Tc-99m Macrosalb

A 49-year-old woman developed an anaphylactic reaction to Tc-99m macrosalb used for pulmonary scintigraphy. The patient received an intravenous injection of Tc-99m macrosalb 120 MBq, containing macroaggregates of human albumin 0.14 mg. Within 1 min she developed itching all over her body, an itching...

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Detalles Bibliográficos
Autores principales: Schreuder, Nanno, de Hoog, Quincy, van der Bruggen, Wouter, van Puijenbroek, Eugène P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401020/
https://www.ncbi.nlm.nih.gov/pubmed/30838475
http://dx.doi.org/10.1007/s40800-019-0097-4
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author Schreuder, Nanno
de Hoog, Quincy
van der Bruggen, Wouter
van Puijenbroek, Eugène P.
author_facet Schreuder, Nanno
de Hoog, Quincy
van der Bruggen, Wouter
van Puijenbroek, Eugène P.
author_sort Schreuder, Nanno
collection PubMed
description A 49-year-old woman developed an anaphylactic reaction to Tc-99m macrosalb used for pulmonary scintigraphy. The patient received an intravenous injection of Tc-99m macrosalb 120 MBq, containing macroaggregates of human albumin 0.14 mg. Within 1 min she developed itching all over her body, an itching throat and dyspnoea. This was followed by urticaria and facial oedema. She was diagnosed with an anaphylactic shock. The patient received clemastine and prednisone, and fully recovered after release from the hospital. According to the Naranjo assessment algorithm, the relationship between the allergic reaction and the administration of Tc-99m macrosalb should be considered as ‘probable’.
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spelling pubmed-64010202019-03-22 Anaphylactic Reaction to Tc-99m Macrosalb Schreuder, Nanno de Hoog, Quincy van der Bruggen, Wouter van Puijenbroek, Eugène P. Drug Saf Case Rep Case Report A 49-year-old woman developed an anaphylactic reaction to Tc-99m macrosalb used for pulmonary scintigraphy. The patient received an intravenous injection of Tc-99m macrosalb 120 MBq, containing macroaggregates of human albumin 0.14 mg. Within 1 min she developed itching all over her body, an itching throat and dyspnoea. This was followed by urticaria and facial oedema. She was diagnosed with an anaphylactic shock. The patient received clemastine and prednisone, and fully recovered after release from the hospital. According to the Naranjo assessment algorithm, the relationship between the allergic reaction and the administration of Tc-99m macrosalb should be considered as ‘probable’. Springer International Publishing 2019-03-05 /pmc/articles/PMC6401020/ /pubmed/30838475 http://dx.doi.org/10.1007/s40800-019-0097-4 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Case Report
Schreuder, Nanno
de Hoog, Quincy
van der Bruggen, Wouter
van Puijenbroek, Eugène P.
Anaphylactic Reaction to Tc-99m Macrosalb
title Anaphylactic Reaction to Tc-99m Macrosalb
title_full Anaphylactic Reaction to Tc-99m Macrosalb
title_fullStr Anaphylactic Reaction to Tc-99m Macrosalb
title_full_unstemmed Anaphylactic Reaction to Tc-99m Macrosalb
title_short Anaphylactic Reaction to Tc-99m Macrosalb
title_sort anaphylactic reaction to tc-99m macrosalb
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401020/
https://www.ncbi.nlm.nih.gov/pubmed/30838475
http://dx.doi.org/10.1007/s40800-019-0097-4
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