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PLD-dependent phosphatidic acid microdomains are signaling platforms for podosome formation

Local membrane phospholipid enrichment serves as docking platform for signaling proteins involved in many processes including cell adhesion and migration. Tissue-resident dendritic cells (DCs) assemble actomyosin-based structures called podosomes, which mediate adhesion and degradation of extracellu...

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Detalles Bibliográficos
Autores principales: Bolomini-Vittori, Matteo, Mennens, Svenja F. B., Joosten, Ben, Fransen, Jack, Du, Guangwei, van den Dries, Koen, Cambi, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401089/
https://www.ncbi.nlm.nih.gov/pubmed/30837487
http://dx.doi.org/10.1038/s41598-019-39358-0