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PLD-dependent phosphatidic acid microdomains are signaling platforms for podosome formation
Local membrane phospholipid enrichment serves as docking platform for signaling proteins involved in many processes including cell adhesion and migration. Tissue-resident dendritic cells (DCs) assemble actomyosin-based structures called podosomes, which mediate adhesion and degradation of extracellu...
Autores principales: | Bolomini-Vittori, Matteo, Mennens, Svenja F. B., Joosten, Ben, Fransen, Jack, Du, Guangwei, van den Dries, Koen, Cambi, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401089/ https://www.ncbi.nlm.nih.gov/pubmed/30837487 http://dx.doi.org/10.1038/s41598-019-39358-0 |
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