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Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation
Lysine acetylation is a reversible posttranslational modification that occurs at thousands of sites on human proteins. However, the stoichiometry of acetylation remains poorly characterized, and is important for understanding acetylation-dependent mechanisms of protein regulation. Here we provide ac...
Autores principales: | Hansen, Bogi Karbech, Gupta, Rajat, Baldus, Linda, Lyon, David, Narita, Takeo, Lammers, Michael, Choudhary, Chunaram, Weinert, Brian T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401094/ https://www.ncbi.nlm.nih.gov/pubmed/30837475 http://dx.doi.org/10.1038/s41467-019-09024-0 |
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