B-cell depletion induces a shift in self antigen specific B-cell repertoire and cytokine pattern in patients with bullous pemphigoid

Bullous Pemphigoid is the most common auto-immune bullous skin disease. It is characterized by the production of auto-antibodies directed against 2 proteins of the hemi-desmosome (BP180 and BP230). We assessed the efficacy and mechanisms of action of rituximab, an anti-CD20 monoclonal antibody, in 1...

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Detalles Bibliográficos
Autores principales: Berkani, Nicolas, Joly, Pascal, Golinski, Marie-Laure, Colliou, Natacha, Lim, Annick, Larbi, Anis, Riou, Gaetan, Caillot, Frederique, Bernard, Philippe, Bedane, Christophe, Delaporte, Emmanuel, Chaby, Guillaume, Dompmartin, Anne, Hertl, Michael, Calbo, Sebastien, Musette, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401188/
https://www.ncbi.nlm.nih.gov/pubmed/30837635
http://dx.doi.org/10.1038/s41598-019-40203-7

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