Cargando…

Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton

APOL1-miR193a axis participates in the preservation of molecular phenotype of differentiated podocytes (DPDs). We examined the hypothesis that APOL1 (G0) preserves, but APOL1 risk alleles (G1 and G2) disrupt APOL1-miR193a axis in DPDs. DPDG0s displayed down-regulation of miR193a, but upregulation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Vinod, Paliwal, Nitpriya, Ayasolla, Kamesh, Vashistha, Himanshu, Jha, Alok, Chandel, Nirupama, Chowdhary, Sheetal, Saleem, Moin A., Malhotra, Ashwani, Chander, Praveen N., Skorecki, Karl, Singhal, Pravin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401370/ https://www.ncbi.nlm.nih.gov/pubmed/30837512 http://dx.doi.org/10.1038/s41598-019-39376-y

Ejemplares similares

MiR193a Modulation and Podocyte Phenotype †
por: Jha, Alok, et al.
Publicado: (2020)

Impact of APOL1 polymorphism and IL-1β priming in the entry and persistence of HIV-1 in human podocytes
por: Mikulak, Joanna, et al.
Publicado: (2016)

Effect of APOL1 disease risk variants on APOL1 gene product
por: Haque, Shabirul, et al.
Publicado: (2017)

APOL1 risk variants cause podocytes injury through enhancing endoplasmic reticulum stress
por: Wen, Hongxiu, et al.
Publicado: (2018)

APOL1 polymorphism modulates sphingolipid profile of human podocytes
por: Valsecchi, Manuela, et al.
Publicado: (2020)

Morphine Induces Albuminuria by Compromising Podocyte Integrity
por: Lan, Xiqian, et al.
Publicado: (2013)

Apolipoprotein L1 (APOL1) Variants (Vs) a possible link between Heroin-associated Nephropathy (HAN) and HIV-associated Nephropathy (HIVAN)
por: Lan, Xiqian, et al.
Publicado: (2015)

Vitamin D receptor and epigenetics in HIV infection and drug abuse
por: Chandel, Nirupama, et al.
Publicado: (2015)

The podocyte cytoskeleton in health and in disease
por: Mathieson, Peter W.
Publicado: (2012)

Regulation of the Actin Cytoskeleton in Podocytes
por: Blaine, Judith, et al.
Publicado: (2020)

Transcriptomic Analysis of Human Podocytes In Vitro: Effects of Differentiation and APOL1 Genotype
por: Yoshida, Teruhiko, et al.
Publicado: (2022)

APOL1 renal risk variants exacerbate podocyte injury by increasing inflammatory stress
por: Wakashin, Hidefumi, et al.
Publicado: (2020)

Comparative Analysis of the APOL1 Variants in the Genetic Landscape of Renal Carcinoma Cells
por: Tzukerman, Maty, et al.
Publicado: (2022)

Nicotine Induces Podocyte Apoptosis through Increasing Oxidative Stress
por: Lan, Xiqian, et al.
Publicado: (2016)

APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy
por: Bruggeman, Leslie A., et al.
Publicado: (2019)

Parietal Epithelial Cell Behavior and Its Modulation by microRNA-193a
por: Bharati, Joyita, et al.
Publicado: (2023)

Endoplasmic reticulum-translocation is essential for APOL1 cellular toxicity
por: Kruzel-Davila, Etty, et al.
Publicado: (2021)

Levamisole Modulation of Podocytes’ Actin Cytoskeleton in Nephrotic Syndrome
por: Veissi, Susan T., et al.
Publicado: (2023)

Beta Adrenergic Overstimulation Impaired Vascular Contractility via Actin-Cytoskeleton Disorganization in Rabbit Cerebral Artery
por: Kim, Hyoung Kyu, et al.
Publicado: (2012)

Tacrolimus Protects Podocytes from Injury in Lupus Nephritis Partly by Stabilizing the Cytoskeleton and Inhibiting Podocyte Apoptosis
por: Liao, Ruyi, et al.
Publicado: (2015)

RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signal
por: Huang, Zongshun, et al.
Publicado: (2016)

Cytoskeleton Rearrangements Modulate TRPC6 Channel Activity in Podocytes
por: Shalygin, Alexey, et al.
Publicado: (2021)

Novel Human Podocyte Cell Model Carrying G2/G2 APOL1 High-Risk Genotype
por: Ekulu, Pepe M., et al.
Publicado: (2021)

The disorganized personality
por: Kisker, George W.
Publicado: (1964)

Proteinuric Kidney Diseases: A Podocyte's Slit Diaphragm and Cytoskeleton Approach
por: Yu, Samuel Mon-Wei, et al.
Publicado: (2018)

L-Carnitine Mitigates Oxidative Stress and Disorganization of Cytoskeleton Intermediate Filaments in Cisplatin-Induced Hepato-Renal Toxicity in Rats
por: Elkomy, Ashraf, et al.
Publicado: (2020)

Filming disorganized attachment
por: Duschinsky, Robbie, et al.
Publicado: (2016)

Symptoms of Social Disorganization
por: Hull, Theo. Y.
Publicado: (1915)

Disorganization, COMT, and Children's Social Behavior: The Norwegian Hypothesis of Legacy of Disorganized Attachment
por: Li, Zhi, et al.
Publicado: (2016)

Epidemiology and the Impact of Acute Kidney Injury on Outcomes in Patients with Rhabdomyolysis
por: Yang, Chien-Wen, et al.
Publicado: (2021)

CRISPR/Cas9-mediated deletion of the Wiskott-Aldrich syndrome locus causes actin cytoskeleton disorganization in murine erythroleukemia cells
por: Fernández-Calleja, Vanessa, et al.
Publicado: (2019)

5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Aβ peptide-induced inflammatory mediators in astroglia
por: Ayasolla, Kamesh R, et al.
Publicado: (2005)

Catalpol Ameliorates Podocyte Injury by Stabilizing Cytoskeleton and Enhancing Autophagy in Diabetic Nephropathy
por: Chen, Yan, et al.
Publicado: (2019)

Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes
por: Wang, Hong, et al.
Publicado: (2021)

Nucleosomal dsDNA Stimulates APOL1 Expression in Human Cultured Podocytes by Activating the cGAS/IFI16-STING Signaling Pathway
por: Davis, Shamara E., et al.
Publicado: (2019)

Current concepts of the podocyte in nephrotic syndrome
por: Ding, Wen Y., et al.
Publicado: (2012)

Marsyas und apoll : fur flöte ünd klavier /
por: Muench, Gerhart, 1907-1988
Publicado: (1991)

HIV Viremia Is Associated With APOL1 Variants and Reduced JC-Viruria
por: Kruzel-Davila, Etty, et al.
Publicado: (2021)

APOL1 Kidney-Risk Variants Induce Mitochondrial Fission
por: Ma, Lijun, et al.
Publicado: (2020)

Renal Lipotoxicity-Associated Inflammation and Insulin Resistance Affects Actin Cytoskeleton Organization in Podocytes
por: Martínez-García, Cristina, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_20jrlihh14dolrthaqkv6n6a5s