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Cytohesin-3 is required for full insulin receptor signaling and controls body weight via lipid excretion
Insulin plays a central role in regulating metabolic homeostasis and guanine-nucleotide exchange factors of the cytohesin family have been suggested to be involved in insulin signal transduction. The Drosophila homolog of cytohesin-3, steppke, has been shown to be essential for insulin signaling dur...
Autores principales: | Jux, Bettina, Gosejacob, Dominic, Tolksdorf, Felix, Mandel, Christa, Rieck, Michael, Namislo, Angrit, Pfeifer, Alexander, Kolanus, Waldemar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401384/ https://www.ncbi.nlm.nih.gov/pubmed/30837656 http://dx.doi.org/10.1038/s41598-019-40231-3 |
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