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The Human CD4(+) T Cell Response against Mumps Virus Targets a Broadly Recognized Nucleoprotein Epitope

Mumps outbreaks among vaccinated young adults stress the need for a better understanding of mumps virus (MuV)-induced immunity. Antibody responses to MuV are well characterized, but studies on T cell responses are limited. We recently isolated a MuV-specific CD4(+) T cell clone by stimulating periph...

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Detalles Bibliográficos
Autores principales: de Wit, Jelle, Emmelot, Maarten E., Poelen, Martien C. M., Lanfermeijer, Josien, Han, Wanda G. H., van Els, Cécile A. C. M., Kaaijk, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401470/
https://www.ncbi.nlm.nih.gov/pubmed/30626672
http://dx.doi.org/10.1128/JVI.01883-18