Cargando…

Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer

Rationale: Triple-negative breast cancer (TNBC) is characterized by the absence of estrogen receptor alpha (ER-α), human epidermal growth factor receptor 2 (HER2) and progesterone receptor (PR) expression, but the effect of lacking the three factors on TNBC is unclear. Whether loss of the three fact...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Zitong, Li, Lin, Du, Peina, Ma, Liying, Zhang, Weimin, Zheng, Leilei, Lan, Bo, Zhang, Bailin, Ma, Fei, Xu, Bo, Zhan, Qimin, Song, Yongmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401504/ https://www.ncbi.nlm.nih.gov/pubmed/30867840 http://dx.doi.org/10.7150/thno.30701

Ejemplares similares

Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer: Erratum
por: Zhao, Zitong, et al.
Publicado: (2023)

Downregulation of miR-503 Promotes ESCC Cell Proliferation, Migration, and Invasion by Targeting Cyclin D1
por: Jiang, Lanfang, et al.
Publicado: (2017)

Echinacoside Suppresses the Progression of Breast Cancer by Downregulating the Expression of miR-4306 and miR-4508
por: Bian, Peng, et al.
Publicado: (2021)

Tumor-derived miR-20b-5p promotes lymphatic metastasis of esophageal squamous cell carcinoma by remodeling the tumor microenvironment
por: Zhao, Zitong, et al.
Publicado: (2023)

MiR-3653 blocks autophagy to inhibit epithelial–mesenchymal transition in breast cancer cells by targeting the autophagy-regulatory genes ATG12 and AMBRA1
por: Song, Huachen, et al.
Publicado: (2023)

The chromosome 11q13.3 amplification associated lymph node metastasis is driven by miR-548k through modulating tumor microenvironment
por: Zhang, Weimin, et al.
Publicado: (2018)

PTBP1 promotes IRES-mediated translation of cyclin B1in cancer: PTBP1 promotes IRES-mediated translation of cyclin B1 in cancer
por: Fan, Xinyi, et al.
Publicado: (2022)

TCF7/SNAI2/miR-4306 feedback loop promotes hypertrophy of ligamentum flavum
por: Duan, Yang, et al.
Publicado: (2022)

Crystal structure of the MSMEG_4306 gene product from Mycobacterium smegmatis
por: Kumar, Adarsh, et al.
Publicado: (2018)

4306 Periodontal disease and the oral microbiome in antiretroviral-treated patients with HIV
por: Annavajhala, Medini K, et al.
Publicado: (2020)

The miR-4306/IGF2R axis modulates the lung adenocarcinoma response to irradiation in vitro and in vivo
por: Liu, Lipin, et al.
Publicado: (2021)

miR-4306 inhibits the malignant behaviors of colorectal cancer by regulating lncRNA FoxD2-AS1
por: Ye, Jinjun, et al.
Publicado: (2021)

miR-629-3p may serve as a novel biomarker and potential therapeutic target for lung metastases of triple-negative breast cancer
por: Wang, Jin, et al.
Publicado: (2017)

Regulation of capillary tubules and lipid formation in vascular endothelial cells and macrophages via extracellular vesicle-mediated microRNA-4306 transfer
por: Yang, Ying, et al.
Publicado: (2018)

Migfilin Protein Promotes Migration and Invasion in Human Glioma through Epidermal Growth Factor Receptor-mediated Phospholipase C-γ and STAT3 Protein Signaling Pathways
por: Ou, Yunwei, et al.
Publicado: (2012)

Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl‐2/caspase‐3 pathway
por: Gao, Xiaohan, et al.
Publicado: (2021)

MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer
por: Xu, Xin, et al.
Publicado: (2016)

Inhibition of miR-214 attenuates the migration and invasion of triple-negative breast cancer cells
por: Zhang, Yi, et al.
Publicado: (2019)

Long noncoding RNA ILF3-AS1 aggravates papillary thyroid carcinoma progression via regulating the miR-4306/PLAGL2 axis
por: Zeng, Zhaohui, et al.
Publicado: (2021)

Chrysin serves as a novel inhibitor of DGKα/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma (ESCC)
por: Chen, Jie, et al.
Publicado: (2021)

Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1
por: Xiao, Wenchang, et al.
Publicado: (2021)

Deregulated expression and subcellular localization of CPSF6, a circRNA-binding protein, promote malignant development of esophageal squamous cell carcinoma
por: Guo, Shichao, et al.
Publicado: (2022)

XPC exon15 Lys939Gln variant increase susceptibility to prostate adenocarcinoma: Evidence based on 4306 patients and 4779 controls
por: Qin, Feng, et al.
Publicado: (2020)

circUSP42 Is Downregulated in Triple-Negative Breast Cancer and Associated With Poor Prognosis
por: Yu, Jinling, et al.
Publicado: (2020)

Extracellular vesicles carrying miR-6836 derived from resistant tumor cells transfer cisplatin resistance of epithelial ovarian cancer via DLG2-YAP1 signaling pathway
por: Zou, Yazhu, et al.
Publicado: (2023)

Cantharidin induces apoptosis of human triple negative breast cancer cells through mir-607-mediated downregulation of EGFR
por: Yang, Tianfeng, et al.
Publicado: (2023)

The Biological Function of TUSC7/miR-1224-3p Axis in Triple-Negative Breast Cancer
por: Zheng, Bo-Hao, et al.
Publicado: (2021)

LncRNA PAPAS may promote triple-negative breast cancer by downregulating miR-34a
por: Kong, Yan, et al.
Publicado: (2019)

Targeting hyperactivated DNA-PKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling
por: Lan, Tian, et al.
Publicado: (2016)

Interfering MSN-NONO complex–activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer
por: Qin, Yuanyuan, et al.
Publicado: (2020)

Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo
por: Zhang, Lan, et al.
Publicado: (2017)

CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer
por: Liu, Xuefeng, et al.
Publicado: (2012)

FOXC1-induced LINC01123 acts as a mediator in triple negative breast cancer
por: Zhang, Purong, et al.
Publicado: (2020)

SYTL4 downregulates microtubule stability and confers paclitaxel resistance in triple-negative breast cancer
por: Liu, Xi-Yu, et al.
Publicado: (2020)

Kindlin-2 interacts with β-catenin and YB-1 to enhance EGFR transcription during glioma progression
por: Ou, Yunwei, et al.
Publicado: (2016)

Long non‑coding RNA PTCSC3 suppresses triple‑negative breast cancer by downregulating long non‑coding RNA MIR100HG
por: Zhang, Guojun, et al.
Publicado: (2023)

Silence of α1-Antitrypsin Inhibits Migration and Proliferation of Triple Negative Breast Cancer Cells
por: Zhao, Zhijing, et al.
Publicado: (2018)

MiR-25-3p Serves as an Oncogenic MicroRNA by Downregulating the Expression of Merlin in Osteosarcoma
por: Rao, Hua-chun, et al.
Publicado: (2020)

Identification of second primary tumors from lung metastases in patients with esophageal squamous cell carcinoma using whole-exome sequencing
por: Xue, Liyan, et al.
Publicado: (2020)

A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway
por: Yuan, Hongyu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t1jfooqdm9hf2l5uts8figb8ip