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Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme

Glioblastoma multiforme (GBM) has been considered the most aggressive glioma type. Temozolomide (TMZ) is the main first-line chemotherapeutic agent for GBM. Decreased mutS homolog 6 (MSH6) expression is clinically recognized as one of the principal reasons for GBM resistance to TMZ. However, the spe...

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Detalles Bibliográficos
Autores principales: Chen, Yaodong, Liu, Pengfei, Sun, Peng, Jiang, Jian, Zhu, Yuanbo, Dong, Tianxiu, Cui, Yingzhe, Tian, Yuan, An, Tingting, Zhang, Jiuwei, Li, Zizhuo, Yang, Xiuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401508/
https://www.ncbi.nlm.nih.gov/pubmed/30867843
http://dx.doi.org/10.7150/thno.29987