Drug Repositioning Inferred from E2F1-Coregulator Interactions Studies for the Prevention and Treatment of Metastatic Cancers

Metastasis management remains a long-standing challenge. High abundance of E2F1 triggers tumor progression by developing protein-protein interactions (PPI) with coregulators that enhance its potential to activate a network of prometastatic transcriptional targets. Methods: To identify E2F1-coregulat...

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Detalles Bibliográficos
Autores principales: Goody, Deborah, Gupta, Shailendra K., Engelmann, David, Spitschak, Alf, Marquardt, Stephan, Mikkat, Stefan, Meier, Claudia, Hauser, Charlotte, Gundlach, Jan-Paul, Egberts, Jan-Hendrik, Martin, Hubert, Schumacher, Toni, Trauzold, Anna, Wolkenhauer, Olaf, Logotheti, Stella, Pützer, Brigitte M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401510/
https://www.ncbi.nlm.nih.gov/pubmed/30867845
http://dx.doi.org/10.7150/thno.29546

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