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Structure‐Activity Relationship of Hetarylpropylguanidines Aiming at the Development of Selective Histamine Receptor Ligands(†)

New classes of alkylated hetarylpropylguanidines with different functionality and variation in spacer length were synthesized to determine their behavior at the four histamine receptor (H(1)R, H(2)R, H(3)R, H(4)R) subtypes. Alkylated guanidines with different terminal functional groups and varied ba...

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Detalles Bibliográficos
Autores principales: Pockes, Steffen, Wifling, David, Buschauer, Armin, Elz, Sigurd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401531/
https://www.ncbi.nlm.nih.gov/pubmed/30886786
http://dx.doi.org/10.1002/open.201900011