CAAP48, a New Sepsis Biomarker, Induces Hepatic Dysfunction in an in vitro Liver-on-Chip Model

Sepsis is a leading cause of mortality in the critically ill, characterized by life-threatening organ dysfunctions due to dysregulation of the host response to infection. Using mass spectrometry, we identified a C-terminal fragment of alpha-1-antitrypsin, designated CAAP48, as a new sepsis biomarker...

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Detalles Bibliográficos
Autores principales: Blaurock-Möller, Nancy, Gröger, Marko, Siwczak, Fatina, Dinger, Julia, Schmerler, Diana, Mosig, Alexander S., Kiehntopf, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401602/
https://www.ncbi.nlm.nih.gov/pubmed/30873161
http://dx.doi.org/10.3389/fimmu.2019.00273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401602/
https://www.ncbi.nlm.nih.gov/pubmed/30873161
http://dx.doi.org/10.3389/fimmu.2019.00273

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