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Design of Oligonucleotide Carriers: Importance of Polyamine Chain Length

Amine containing polymers are extensively studied as special carriers for short-chain RNA (13–25 nucleotides), which are applied as gene silencing agents in gene therapy of various diseases including cancer. Elaboration of the oligonucleotide carriers requires knowledge about peculiarities of the ol...

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Detalles Bibliográficos
Autores principales: Annenkov, Vadim V., Krishnan, Uma Maheswari, Pal’shin, Viktor A., Zelinskiy, Stanislav N., Kandasamy, Gayathri, Danilovtseva, Elena N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401700/
https://www.ncbi.nlm.nih.gov/pubmed/30961222
http://dx.doi.org/10.3390/polym10121297