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The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2: a phosphatidylserine flippase
Type IV P-type ATPases (P4 ATPases) are lipid flippases that catalyze phospholipid transport from the exoplasmic to the cytoplasmic leaflet of cellular membranes, but the mechanism by which they recognize and transport phospholipids through the lipid bilayer remains unknown. In the present study, we...
Autores principales: | Theorin, Lisa, Faxén, Kristina, Sørensen, Danny Mollerup, Migotti, Rebekka, Dittmar, Gunnar, Schiller, Jürgen, Daleke, David L., Palmgren, Michael, López-Marqués, Rosa Laura, Günther Pomorski, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402034/ https://www.ncbi.nlm.nih.gov/pubmed/30755463 http://dx.doi.org/10.1042/BCJ20180891 |
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