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A fruit fly model for studying paclitaxel-induced peripheral neuropathy and hyperalgesia

Background: Paclitaxel-induced peripheral neuropathy is a common and limiting side effect of an approved and effective chemotherapeutic agent. The cause of this nociception is still unknown. Methods: To uncover the mechanism involved in paclitaxel-induced pain, we developed a Drosophila thermal noci...

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Detalles Bibliográficos
Autores principales: Hamoudi, Zina, Khuong, Thang Manh, Cole, Tiffany, Neely, G. Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402077/
https://www.ncbi.nlm.nih.gov/pubmed/30863531
http://dx.doi.org/10.12688/f1000research.13581.2