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Optimization of secretion and surface localization of heterologous OVA protein in mycobacteria by using LipY as a carrier
BACKGROUND: Mycobacterium bovis Bacille Calmette-Guérin (BCG) is not only used as a vaccine against tuberculosis but also protects against leprosy and is used as part of bladder cancer treatment to induce a protective immune response. However, protection by BCG vaccination is not optimal. To improve...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402100/ https://www.ncbi.nlm.nih.gov/pubmed/30841891 http://dx.doi.org/10.1186/s12934-019-1093-1 |