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Impact of c-MYC expression on proliferation, differentiation, and risk of neoplastic transformation of human mesenchymal stromal cells

BACKGROUND: Mesenchymal stromal cells isolated from bone marrow (MSC) represent an attractive source of adult stem cells for regenerative medicine. However, thorough research is required into their clinical application safety issues concerning a risk of potential neoplastic degeneration in a process...

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Detalles Bibliográficos
Autores principales:	Melnik, Svitlana, Werth, Nadine, Boeuf, Stephane, Hahn, Eva-Maria, Gotterbarm, Tobias, Anton, Martina, Richter, Wiltrud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402108/ https://www.ncbi.nlm.nih.gov/pubmed/30836996 http://dx.doi.org/10.1186/s13287-019-1187-z

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