Kinesin-1 Regulates Extrasynaptic Targeting of NMDARs and Neuronal Vulnerability Toward Excitotoxicity

N-methyl-D-aspartate (NMDA) receptor (NMDAR) is highly compartmentalized in neurons, and its dysfunction has been implicated in various neuropsychiatric and neurodegenerative disorders. Recent failure to exploit NMDAR antagonization as a potential therapeutic target has driven the need to identify m...

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Detalles Bibliográficos
Autores principales: Lin, Raozhou, Duan, Zhigang, Sun, Haitao, Fung, Man-Lung, Chen, Hansen, Wang, Jing, Lau, Chi-Fai, Yang, Di, Liu, Yu, Ni, Yanxiang, Wang, Zai, Cui, Ju, Wu, Wutian, Yung, Wing-Ho, Chan, Ying-Shing, Lo, Amy C.Y., Xia, Jun, Shen, Jiangang, Huang, Jian-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402234/
https://www.ncbi.nlm.nih.gov/pubmed/30826728
http://dx.doi.org/10.1016/j.isci.2019.02.009

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