Cargando…

A Homing System Targets Therapeutic T-cells to Brain Cancer

Successful T-cell immunotherapy for brain cancer should adequately access tumor tissues, but strategies to achieve this have been elusive. We discovered that, in contrast to inflammatory brain diseases, such as multiple sclerosis, where endothelial-cells upregulate ICAM1 and VCAM1 to guide the extra...

Descripción completa

Detalles Bibliográficos
Autores principales: Samaha, Heba, Pignata, Antonella, Fousek, Kristen, Ren, Jun, Lam, Fong, Stossi, Fabio, Dubrulle, Julien, Salsman, Vita S, Krishnan, Shanmugarajan, Hong, Sung-Ha, Baker, Matthew L, Shree, Ankita, Gad, Ahmed Z, Shum, Thomas, Fukumura, Dai, Byrd, Tiara T., Mukherjee, Malini, Marrelli, Sean P., Orange, Jordan S, Joseph, Sujith K., Sorensen, Poul H., Taylor, Michael D, Hegde, Meenakshi, Mamonkin, Maksim, Jain, Rakesh K, El-Naggar, Shahenda, Ahmed, Nabil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402337/
https://www.ncbi.nlm.nih.gov/pubmed/30185905
http://dx.doi.org/10.1038/s41586-018-0499-y