Self‐Assembly: Targeted Therapy against Metastatic Melanoma Based on Self‐Assembled Metal‐Phenolic Nanocomplexes Comprised of Green Tea Catechin (Adv. Sci. 5/2019)

The targeted therapy of metastatic melanoma is a highly challenging therapeutic goal that has received only limited attention to date. In article number 1801688, Junling Guo, Xuepin Liao, and co‐workers report the self‐assembly of therapeutic nanocomplexes composed of green tea polyphenols, epigallo...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ke, Xiao, Gao, Richardson, Joseph J., Tardy, Blaise L., Ejima, Hirotaka, Huang, Wen, Guo, Junling, Liao, Xuepin, Shi, Bi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Frontispiece
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402404/
http://dx.doi.org/10.1002/advs.201970028
Descripción
Sumario:The targeted therapy of metastatic melanoma is a highly challenging therapeutic goal that has received only limited attention to date. In article number 1801688, Junling Guo, Xuepin Liao, and co‐workers report the self‐assembly of therapeutic nanocomplexes composed of green tea polyphenols, epigallocatechin‐3‐gallate (EGCG), and lanthanide metal ions (Sm(3+)). These nanocomplexes show remarkable targeted therapy against melanoma and prevent aggressive migration to main organs with no adverse side effects. [Image: see text]

Ejemplares similares