Cargando…
Self‐Assembly: Targeted Therapy against Metastatic Melanoma Based on Self‐Assembled Metal‐Phenolic Nanocomplexes Comprised of Green Tea Catechin (Adv. Sci. 5/2019)
The targeted therapy of metastatic melanoma is a highly challenging therapeutic goal that has received only limited attention to date. In article number 1801688, Junling Guo, Xuepin Liao, and co‐workers report the self‐assembly of therapeutic nanocomplexes composed of green tea polyphenols, epigallo...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402404/ http://dx.doi.org/10.1002/advs.201970028 |
_version_ | 1783400390972145664 |
---|---|
author | Li, Ke Xiao, Gao Richardson, Joseph J. Tardy, Blaise L. Ejima, Hirotaka Huang, Wen Guo, Junling Liao, Xuepin Shi, Bi |
author_facet | Li, Ke Xiao, Gao Richardson, Joseph J. Tardy, Blaise L. Ejima, Hirotaka Huang, Wen Guo, Junling Liao, Xuepin Shi, Bi |
author_sort | Li, Ke |
collection | PubMed |
description | The targeted therapy of metastatic melanoma is a highly challenging therapeutic goal that has received only limited attention to date. In article number 1801688, Junling Guo, Xuepin Liao, and co‐workers report the self‐assembly of therapeutic nanocomplexes composed of green tea polyphenols, epigallocatechin‐3‐gallate (EGCG), and lanthanide metal ions (Sm(3+)). These nanocomplexes show remarkable targeted therapy against melanoma and prevent aggressive migration to main organs with no adverse side effects. [Image: see text] |
format | Online Article Text |
id | pubmed-6402404 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-64024042019-03-18 Self‐Assembly: Targeted Therapy against Metastatic Melanoma Based on Self‐Assembled Metal‐Phenolic Nanocomplexes Comprised of Green Tea Catechin (Adv. Sci. 5/2019) Li, Ke Xiao, Gao Richardson, Joseph J. Tardy, Blaise L. Ejima, Hirotaka Huang, Wen Guo, Junling Liao, Xuepin Shi, Bi Adv Sci (Weinh) Frontispiece The targeted therapy of metastatic melanoma is a highly challenging therapeutic goal that has received only limited attention to date. In article number 1801688, Junling Guo, Xuepin Liao, and co‐workers report the self‐assembly of therapeutic nanocomplexes composed of green tea polyphenols, epigallocatechin‐3‐gallate (EGCG), and lanthanide metal ions (Sm(3+)). These nanocomplexes show remarkable targeted therapy against melanoma and prevent aggressive migration to main organs with no adverse side effects. [Image: see text] John Wiley and Sons Inc. 2019-03-06 /pmc/articles/PMC6402404/ http://dx.doi.org/10.1002/advs.201970028 Text en © 2019 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Frontispiece Li, Ke Xiao, Gao Richardson, Joseph J. Tardy, Blaise L. Ejima, Hirotaka Huang, Wen Guo, Junling Liao, Xuepin Shi, Bi Self‐Assembly: Targeted Therapy against Metastatic Melanoma Based on Self‐Assembled Metal‐Phenolic Nanocomplexes Comprised of Green Tea Catechin (Adv. Sci. 5/2019) |
title | Self‐Assembly: Targeted Therapy against Metastatic Melanoma Based on Self‐Assembled Metal‐Phenolic Nanocomplexes Comprised of Green Tea Catechin (Adv. Sci. 5/2019) |
title_full | Self‐Assembly: Targeted Therapy against Metastatic Melanoma Based on Self‐Assembled Metal‐Phenolic Nanocomplexes Comprised of Green Tea Catechin (Adv. Sci. 5/2019) |
title_fullStr | Self‐Assembly: Targeted Therapy against Metastatic Melanoma Based on Self‐Assembled Metal‐Phenolic Nanocomplexes Comprised of Green Tea Catechin (Adv. Sci. 5/2019) |
title_full_unstemmed | Self‐Assembly: Targeted Therapy against Metastatic Melanoma Based on Self‐Assembled Metal‐Phenolic Nanocomplexes Comprised of Green Tea Catechin (Adv. Sci. 5/2019) |
title_short | Self‐Assembly: Targeted Therapy against Metastatic Melanoma Based on Self‐Assembled Metal‐Phenolic Nanocomplexes Comprised of Green Tea Catechin (Adv. Sci. 5/2019) |
title_sort | self‐assembly: targeted therapy against metastatic melanoma based on self‐assembled metal‐phenolic nanocomplexes comprised of green tea catechin (adv. sci. 5/2019) |
topic | Frontispiece |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402404/ http://dx.doi.org/10.1002/advs.201970028 |
work_keys_str_mv | AT like selfassemblytargetedtherapyagainstmetastaticmelanomabasedonselfassembledmetalphenolicnanocomplexescomprisedofgreenteacatechinadvsci52019 AT xiaogao selfassemblytargetedtherapyagainstmetastaticmelanomabasedonselfassembledmetalphenolicnanocomplexescomprisedofgreenteacatechinadvsci52019 AT richardsonjosephj selfassemblytargetedtherapyagainstmetastaticmelanomabasedonselfassembledmetalphenolicnanocomplexescomprisedofgreenteacatechinadvsci52019 AT tardyblaisel selfassemblytargetedtherapyagainstmetastaticmelanomabasedonselfassembledmetalphenolicnanocomplexescomprisedofgreenteacatechinadvsci52019 AT ejimahirotaka selfassemblytargetedtherapyagainstmetastaticmelanomabasedonselfassembledmetalphenolicnanocomplexescomprisedofgreenteacatechinadvsci52019 AT huangwen selfassemblytargetedtherapyagainstmetastaticmelanomabasedonselfassembledmetalphenolicnanocomplexescomprisedofgreenteacatechinadvsci52019 AT guojunling selfassemblytargetedtherapyagainstmetastaticmelanomabasedonselfassembledmetalphenolicnanocomplexescomprisedofgreenteacatechinadvsci52019 AT liaoxuepin selfassemblytargetedtherapyagainstmetastaticmelanomabasedonselfassembledmetalphenolicnanocomplexescomprisedofgreenteacatechinadvsci52019 AT shibi selfassemblytargetedtherapyagainstmetastaticmelanomabasedonselfassembledmetalphenolicnanocomplexescomprisedofgreenteacatechinadvsci52019 |