Report of β-lactam antibiotic–induced vancomycin-resistant Staphylococcus aureus from a university hospital in Egypt

We report a case of hospital-acquired pneumonia that to our knowledge is the first description in Egypt of the emergence of vancomycin (VA)-resistant Staphylococcus aureus due to the concomitant use of β-lactams. The combination of β-lactam antibiotics and VA in the treatment of methicillin-resistan...

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Autores principales: Taha, A.E., Badr, M.F., El-Morsy, F.E., Hammad, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
First Clinical Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402424/
https://www.ncbi.nlm.nih.gov/pubmed/30886721
http://dx.doi.org/10.1016/j.nmni.2019.01.003
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author Taha, A.E.
Badr, M.F.
El-Morsy, F.E.
Hammad, E.
author_facet Taha, A.E.
Badr, M.F.
El-Morsy, F.E.
Hammad, E.
author_sort Taha, A.E.
collection PubMed
description We report a case of hospital-acquired pneumonia that to our knowledge is the first description in Egypt of the emergence of vancomycin (VA)-resistant Staphylococcus aureus due to the concomitant use of β-lactams. The combination of β-lactam antibiotics and VA in the treatment of methicillin-resistant S. aureus must be avoided to refrain from inducing VA resistance; further, if there is coinfection with Gram-negative bacilli, β-lactams must be avoided. If β-lactam antibiotic–induced VA-resistant methicillin-resistant S. aureus is isolated, then β-lactams must be avoided until the organism's sensitivity to VA is restored if VA is the only therapeutic option available.
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spelling pubmed-64024242019-03-18 Report of β-lactam antibiotic–induced vancomycin-resistant Staphylococcus aureus from a university hospital in Egypt Taha, A.E. Badr, M.F. El-Morsy, F.E. Hammad, E. New Microbes New Infect First Clinical Case Report We report a case of hospital-acquired pneumonia that to our knowledge is the first description in Egypt of the emergence of vancomycin (VA)-resistant Staphylococcus aureus due to the concomitant use of β-lactams. The combination of β-lactam antibiotics and VA in the treatment of methicillin-resistant S. aureus must be avoided to refrain from inducing VA resistance; further, if there is coinfection with Gram-negative bacilli, β-lactams must be avoided. If β-lactam antibiotic–induced VA-resistant methicillin-resistant S. aureus is isolated, then β-lactams must be avoided until the organism's sensitivity to VA is restored if VA is the only therapeutic option available. Elsevier 2019-01-30 /pmc/articles/PMC6402424/ /pubmed/30886721 http://dx.doi.org/10.1016/j.nmni.2019.01.003 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle First Clinical Case Report
Taha, A.E.
Badr, M.F.
El-Morsy, F.E.
Hammad, E.
Report of β-lactam antibiotic–induced vancomycin-resistant Staphylococcus aureus from a university hospital in Egypt
title Report of β-lactam antibiotic–induced vancomycin-resistant Staphylococcus aureus from a university hospital in Egypt
title_full Report of β-lactam antibiotic–induced vancomycin-resistant Staphylococcus aureus from a university hospital in Egypt
title_fullStr Report of β-lactam antibiotic–induced vancomycin-resistant Staphylococcus aureus from a university hospital in Egypt
title_full_unstemmed Report of β-lactam antibiotic–induced vancomycin-resistant Staphylococcus aureus from a university hospital in Egypt
title_short Report of β-lactam antibiotic–induced vancomycin-resistant Staphylococcus aureus from a university hospital in Egypt
title_sort report of β-lactam antibiotic–induced vancomycin-resistant staphylococcus aureus from a university hospital in egypt
topic First Clinical Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402424/
https://www.ncbi.nlm.nih.gov/pubmed/30886721
http://dx.doi.org/10.1016/j.nmni.2019.01.003
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