Targeting Trop-2 in solid tumors: future prospects

Trop-2 is a transmembrane glycoprotein that is upregulated in all cancer types independent of baseline levels of Trop-2 expression. Trop-2 is an ideal candidate for targeted therapeutics due to it being a transmembrane protein with an extracellular domain overexpressed on a wide variety of tumors as...

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Detalles Bibliográficos
Autores principales: Zaman, Saif, Jadid, Hassan, Denson, Aaron C, Gray, Jhanelle E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402435/
https://www.ncbi.nlm.nih.gov/pubmed/30881031
http://dx.doi.org/10.2147/OTT.S162447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402435/
https://www.ncbi.nlm.nih.gov/pubmed/30881031
http://dx.doi.org/10.2147/OTT.S162447

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