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MALAT1/miR-15b-5p/MAPK1 mediates endothelial progenitor cells autophagy and affects coronary atherosclerotic heart disease via mTOR signaling pathway

Objective: Present study focused on the influence of lncRNA MALAT1 on coronary atherosclerotic heart disease (CAD) by regulating miR-15b-5p/MAPK1 and mTOR signaling pathway. Method: Differentially expressed genes and activated pathway were investigated through bioinformatics analysis. QRT-PCR was co...

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Detalles Bibliográficos
Autores principales: Zhu, Ying, Yang, Tianrui, Duan, Jinlan, Mu, Ninghui, Zhang, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402525/
https://www.ncbi.nlm.nih.gov/pubmed/30787203
http://dx.doi.org/10.18632/aging.101766