Cargando…
Mass Cytometry Analysis Reveals that Specific Intratumoral CD4(+) T Cell Subsets Correlate with Patient Survival in Follicular Lymphoma
Follicular lymphoma (FL) is an indolent B cell malignancy characterized by an extensive but poorly functional T cell infiltrate in the tumor microenvironment. Using mass cytometry, we identified at least 12 subsets of intratumoral CD4(+) T cells, 3 of which were unique to FL biopsies versus control...
Autores principales: | Yang, Zhi-Zhang, Jin Kim, Hyo, Villasboas, Jose C., Price-Troska, Tammy, Jalali, Shahrzad, Wu, Hongyan, Luchtel, Rebecca A., Polley, Mei-Yin C., Novak, Anne J., Ansell, Stephen M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402596/ https://www.ncbi.nlm.nih.gov/pubmed/30784598 http://dx.doi.org/10.1016/j.celrep.2019.01.085 |
Ejemplares similares
-
SIRPα expression delineates subsets of intratumoral monocyte/macrophages with different functional and prognostic impact in follicular lymphoma
por: Chen, Ya-Ping, et al.
Publicado: (2019) -
Expression of LAG-3 defines exhaustion of intratumoral PD-1(+) T cells and correlates with poor outcome in follicular lymphoma
por: Yang, Zhi-Zhang, et al.
Publicado: (2017) -
Expression of KLRG1 and CD127 defines distinct CD8(+) subsets that differentially impact patient outcome in follicular lymphoma
por: Wu, Hongyan, et al.
Publicado: (2021) -
P1215: CHARACTERIZATION AND CLINICAL SIGNIFICANCE OF T FOLLICULAR HELPER SUBSETS IN FOLLICULAR LYMPHOMA
por: Yang, Zhi-Zhang, et al.
Publicado: (2023) -
Reverse signaling via PD-L1 supports malignant cell growth and survival in classical Hodgkin lymphoma
por: Jalali, Shahrzad, et al.
Publicado: (2019)