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Ex vivo-expanded highly purified natural killer cells in combination with temozolomide induce antitumor effects in human glioblastoma cells in vitro
Glioblastoma is the leading malignant glioma with a poor prognosis. This study aimed to investigate the antitumor effects of natural killer cells in combination with temozolomide as the standard chemotherapeutic agent for glioblastoma. Using a simple, feeder-less, and chemically defined culture meth...
Autores principales: | Tanaka, Yoshitaka, Nakazawa, Tsutomu, Nakamura, Mitsutoshi, Nishimura, Fumihiko, Matsuda, Ryosuke, Omoto, Koji, Shida, Yoichi, Murakami, Toshiharu, Nakagawa, Ichiro, Motoyama, Yasushi, Morita, Hiromichi, Tsujimura, Takahiro, Nakase, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402639/ https://www.ncbi.nlm.nih.gov/pubmed/30840664 http://dx.doi.org/10.1371/journal.pone.0212455 |
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