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Swainsonine, an alpha-mannosidase inhibitor, may worsen cervical cancer progression through the increase in myeloid derived suppressor cells population
Cervical cancer, caused by high oncogenic risk Human Papillomavirus (HPV) infection, continues to be a public health problem, mainly in developing countries. Using peptide phage display as a tool to identify potential molecular targets in HPV associated tumors, we identified α-mannosidase, among oth...
Autores principales: | Silveira, Caio Raony Farina, Cipelli, Marcella, Manzine, Carolina, Rabelo-Santos, Silvia Helena, Zeferino, Luiz Carlos, Rodríguez Rodríguez, Gretel, de Assis, Josiane Betim, Hebster, Suellen, Bernadinelli, Isabel, Laginha, Fabio, Boccardo, Enrique, Villa, Luisa Lina, Termini, Lara, Lepique, Ana Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402676/ https://www.ncbi.nlm.nih.gov/pubmed/30840689 http://dx.doi.org/10.1371/journal.pone.0213184 |
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