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Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion

Cyclic nucleotide signalling is a major regulator of malaria parasite differentiation. Phosphodiesterase (PDE) enzymes are known to control cyclic GMP (cGMP) levels in the parasite, but the mechanisms by which cyclic AMP (cAMP) is regulated remain enigmatic. Here, we demonstrate that Plasmodium falc...

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Detalles Bibliográficos
Autores principales:	Flueck, Christian, Drought, Laura G., Jones, Andrew, Patel, Avnish, Perrin, Abigail J., Walker, Eloise M., Nofal, Stephanie D., Snijders, Ambrosius P., Blackman, Michael J., Baker, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402698/ https://www.ncbi.nlm.nih.gov/pubmed/30794532 http://dx.doi.org/10.1371/journal.pbio.3000154

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