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Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function

The homeodomain transcription factor NKX2-5 is known to be essential for both normal heart development and for heart function. But little is yet known about the identities of its downstream effectors or their function during differentiation of cardiac progenitor cells (CPCs). We have used transgenic...

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Detalles Bibliográficos
Autores principales: Dupays, Laurent, Towers, Norma, Wood, Sophie, David, Anna, Stuckey, Daniel J., Mohun, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402701/
https://www.ncbi.nlm.nih.gov/pubmed/30840660
http://dx.doi.org/10.1371/journal.pone.0212992