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The interplay of CDK4 and CDK6 in melanoma

The cyclin-dependent kinases CDK4 and CDK6 promote progression through the cell cycle, where their functions are considered to be redundant. Recent studies have identified an additional role for CDK6 in the transcriptional regulation of cancer-relevant genes such as VEGF-A and EGR1 in hematopoietic...

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Detalles Bibliográficos
Autores principales: Kollmann, Karoline, Briand, Coralie, Bellutti, Florian, Schicher, Nikolaus, Blunder, Stefan, Zojer, Markus, Hoeller, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402717/
https://www.ncbi.nlm.nih.gov/pubmed/30858922
http://dx.doi.org/10.18632/oncotarget.26515