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Epiligament Tissue of the Medial Collateral Ligament in Rat Knee Joint: Ultrastructural Study

Introduction Recent studies stressed the importance of the epiligament in ligament nutrition and healing. While ligaments of the knee joint have been the subject of extensive research, the epiligament of the medial collateral ligament has received only limited attention. The aim of our study was to...

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Autores principales: Georgiev, Georgi P, Iliev, Alexandar, Kotov, Georgi, Nedialkova, Violeta K, Kirkov, Vidin, Landzhov, Boycho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402729/
https://www.ncbi.nlm.nih.gov/pubmed/30868026
http://dx.doi.org/10.7759/cureus.3812
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author Georgiev, Georgi P
Iliev, Alexandar
Kotov, Georgi
Nedialkova, Violeta K
Kirkov, Vidin
Landzhov, Boycho
author_facet Georgiev, Georgi P
Iliev, Alexandar
Kotov, Georgi
Nedialkova, Violeta K
Kirkov, Vidin
Landzhov, Boycho
author_sort Georgiev, Georgi P
collection PubMed
description Introduction Recent studies stressed the importance of the epiligament in ligament nutrition and healing. While ligaments of the knee joint have been the subject of extensive research, the epiligament of the medial collateral ligament has received only limited attention. The aim of our study was to present the ultrastructural morphological features of the epiligament of the medial collateral ligament in a rat knee joint. Materials and methods For the present study, we used eight eight-month-old male Wistar rats. A transmission electron microscopic study of the epiligament was conducted according to standard protocol. Results In the epiligament, we described the presence of fibroblasts with the typical features of protein-synthesizing cells, as well as fibrocytes and adipocytes. We noted an abundance of blood vessels and nerve elements. Collagen fibers were organized in multidirectional bundles. Conclusions Our findings confirm that the cells and structures of the epiligament play an important role in the nutrition and healing of the medial collateral ligament.
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spelling pubmed-64027292019-03-13 Epiligament Tissue of the Medial Collateral Ligament in Rat Knee Joint: Ultrastructural Study Georgiev, Georgi P Iliev, Alexandar Kotov, Georgi Nedialkova, Violeta K Kirkov, Vidin Landzhov, Boycho Cureus Orthopedics Introduction Recent studies stressed the importance of the epiligament in ligament nutrition and healing. While ligaments of the knee joint have been the subject of extensive research, the epiligament of the medial collateral ligament has received only limited attention. The aim of our study was to present the ultrastructural morphological features of the epiligament of the medial collateral ligament in a rat knee joint. Materials and methods For the present study, we used eight eight-month-old male Wistar rats. A transmission electron microscopic study of the epiligament was conducted according to standard protocol. Results In the epiligament, we described the presence of fibroblasts with the typical features of protein-synthesizing cells, as well as fibrocytes and adipocytes. We noted an abundance of blood vessels and nerve elements. Collagen fibers were organized in multidirectional bundles. Conclusions Our findings confirm that the cells and structures of the epiligament play an important role in the nutrition and healing of the medial collateral ligament. Cureus 2019-01-02 /pmc/articles/PMC6402729/ /pubmed/30868026 http://dx.doi.org/10.7759/cureus.3812 Text en Copyright © 2019, Georgiev et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Orthopedics
Georgiev, Georgi P
Iliev, Alexandar
Kotov, Georgi
Nedialkova, Violeta K
Kirkov, Vidin
Landzhov, Boycho
Epiligament Tissue of the Medial Collateral Ligament in Rat Knee Joint: Ultrastructural Study
title Epiligament Tissue of the Medial Collateral Ligament in Rat Knee Joint: Ultrastructural Study
title_full Epiligament Tissue of the Medial Collateral Ligament in Rat Knee Joint: Ultrastructural Study
title_fullStr Epiligament Tissue of the Medial Collateral Ligament in Rat Knee Joint: Ultrastructural Study
title_full_unstemmed Epiligament Tissue of the Medial Collateral Ligament in Rat Knee Joint: Ultrastructural Study
title_short Epiligament Tissue of the Medial Collateral Ligament in Rat Knee Joint: Ultrastructural Study
title_sort epiligament tissue of the medial collateral ligament in rat knee joint: ultrastructural study
topic Orthopedics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402729/
https://www.ncbi.nlm.nih.gov/pubmed/30868026
http://dx.doi.org/10.7759/cureus.3812
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