Malignant Sarcomatous Transformation of Benign Giant Cell Tumor of Bone after Treatment with Denosumab Therapy: A Literature Review of Reported Cases

Giant cell tumor of bone (GCTB) is a biologically benign and locally aggressive tumor that most often affects the epiphyseal and metaphyseal sites of long bones in the young adult population. Overexpression of receptor activator of nuclear factor kappa B ligand (RANKL) by cancerous mesenchymal strom...

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Detalles Bibliográficos
Autores principales: Alaqaili, Sadiq I, Abduljabbar, Abbas M, Altaho, Ali J, Khan, Abdulrahman A, Alherabi, Jawaher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
General Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402735/
https://www.ncbi.nlm.nih.gov/pubmed/30868006
http://dx.doi.org/10.7759/cureus.3792

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