Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells

Aim: Acyl-CoA cholesterol acyltransferase 1 (ACAT1) esterifies free cholesterol to cholesteryl esters (CE), which are subsequently hydrolyzed by neutral cholesterol ester hydrolase 1 (NCEH1). The elimination of ACAT1 in vitro reduces the amounts of CE accumulated in Nceh1-deficient macrophages. The...

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Detalles Bibliográficos
Autores principales: Yamazaki, Hisataka, Takahashi, Manabu, Wakabayashi, Tetsuji, Sakai, Kent, Yamamuro, Daisuke, Takei, Akihito, Takei, Shoko, Nagashima, Shuichi, Yagyu, Hiroaki, Sekiya, Motohiro, Ebihara, Ken, Ishibashi, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402884/
https://www.ncbi.nlm.nih.gov/pubmed/30282838
http://dx.doi.org/10.5551/jat.44040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402884/
https://www.ncbi.nlm.nih.gov/pubmed/30282838
http://dx.doi.org/10.5551/jat.44040

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