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Dynamic Reorganization of the Genome Shapes the Recombination Landscape in Meiotic Prophase
In meiotic prophase, chromosomes are organized into compacted loop arrays to promote homolog pairing and recombination. Here, we probe the architecture of the mouse spermatocyte genome in early and late meiotic prophase using Hi-C. Our data support the established loop-array model of meiotic chromos...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403010/ https://www.ncbi.nlm.nih.gov/pubmed/30778236 http://dx.doi.org/10.1038/s41594-019-0187-0 |