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Znhit1 controls intestinal stem cell maintenance by regulating H2A.Z incorporation

Lgr5+ stem cells are crucial to gut epithelium homeostasis; however, how these cells are maintained is not fully understood. Zinc finger HIT-type containing 1 (Znhit1) is an evolutionarily conserved subunit of the SRCAP chromosome remodeling complex. Currently, the function of Znhit1 in vivo and its...

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Detalles Bibliográficos
Autores principales: Zhao, Bing, Chen, Ying, Jiang, Ning, Yang, Li, Sun, Shenfei, Zhang, Yan, Wen, Zengqi, Ray, Lorraine, Liu, Han, Hou, Guoli, Lin, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403214/
https://www.ncbi.nlm.nih.gov/pubmed/30842416
http://dx.doi.org/10.1038/s41467-019-09060-w