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FGF signal is not required for hepatoblast differentiation of human iPS cells

Human induced pluripotent stem cell-derived hepatocyte-like cells are expected to be utilized in pharmaceutical research and regenerative medicine. In general, human induced pluripotent stem (iPS) cells are differentiated into hepatocyte-like cells through definitive endoderm cells and hepatoblast-l...

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Detalles Bibliográficos
Autores principales: Toba, Yukiko, Kiso, Ayumi, Nakamae, Souichiro, Sakurai, Fuminori, Takayama, Kazuo, Mizuguchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403225/
https://www.ncbi.nlm.nih.gov/pubmed/30842525
http://dx.doi.org/10.1038/s41598-019-40305-2