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L1cam-mediated developmental processes of the nervous system are differentially regulated by proteolytic processing

Normal brain development depends on tight temporal and spatial regulation of connections between cells. Mutations in L1cam, a member of the immunoglobulin (Ig) superfamily that mediate cell-cell contacts through homo- and heterophilic interactions, are associated with several developmental abnormali...

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Detalles Bibliográficos
Autores principales: Linneberg, Cecilie, Toft, Christian Liebst Frisk, Kjaer-Sorensen, Kasper, Laursen, Lisbeth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403279/
https://www.ncbi.nlm.nih.gov/pubmed/30842511
http://dx.doi.org/10.1038/s41598-019-39884-x